Watch Grey's Anatomy Season 5
 | Season 5, Episode 1: Dream a Little Dream of MeOriginal Air Date—25 September 2008Meredith and Derek find that "happily ever after" isn't as easy as they hoped, Cristina finds interest in a military doctor, and the Chief is surprised to hear that Seattle Grace is no longer ranked as a top-tier teaching hospital. |
 | Season 5, Episode 2: Here Comes the FloodOriginal Air Date—9 October 2008Determined to reverse Seattle Grace's slide into mediocrity, the chief lays down some new rules for interns and residents with which no one's happy. Derek asks Meredith for further changes in her living arrangements. Lexie challenges Cristina's diagnosis for a patient with a persistent headache, and the chief's preoccupation with reputation blinds him to problems with the physical plant. |
 | Season 5, Episode 3: Brave New WorldOriginal Air Date—16 October 2008Calllie worries over her first real date with Erica. Cristina stumbles upon a neglected area of the hospital. |
 | Season 5, Episode 4: There's No 'I' in TeamOriginal Air Date—23 October 2008Bailey's dream of a domino surgery is scuppered when one of the donors learns of her husband's affair, and Meredith is insulted when she gets no credit for the procedure she and Derek worked on together. |
 | Season 5, Episode 5: Life During WartimeOriginal Air Date—30 October 2008The new trauma surgeon shocks everyone with his methods, Bailey is asked to save a girl with an inoperable tumor, and Callie's not sure what she wants. |
 | Season 5, Episode 6: Rise UpOriginal Air Date—6 November 2008The residents and interns squabbling over procedures upsets Dr. Hunt, Erica discovers what happened to the heart she lost, and Derek asks Sloan to break out the McSteamy to distract Yang. |
 | Season 5, Episode 7: These Ties That BindOriginal Air Date—13 November 2008Izzie wrestles with her ghost, Torres uses a ground-breaking procedure to get her mind off of Hahn, and the interns continue teaching themselves spurred on by a new cohort. |
 | Season 5, Episode 8: In the Midnight HourOriginal Air Date—20 November 2008Sadie manipulates the interns into performing a procedure that goes horribly wrong, Izzie's ghost refuses to leave, and Mark bonds with a girl who's taken responsibility for her sleep-walking father. |
 | Season 5, Episode 9: All by MyselfOriginal Air Date—4 December 2008The residents make their cases for the solo surgery, Sadie chaffs at her restrictions, and Sloan battles his desires. |
Season 5, Episode 10: Wish You Were HereOriginal Air Date—8 January 2009Derek has trouble with objectivity concerning his death row patient, Cristina and Meredith continue their feud, Izzie confides her problem to Alex, and the Chief faces what's become of his life's work. |
 | Season 5, Episode 11: Sympathy for the DevilOriginal Air Date—15 January 2009Derek's mother visits, the death row patient starts angling for death in the hospital, Izzie craves more in her relationships, and Jackson's need for organs becomes critical. |
 | Season 5, Episode 12: Stairway to HeavenOriginal Air Date—22 January 2009Meredith and Miranda each cross a line, William Dunn regrets his decision and Izzie finally confronts what Denny's appearance means. |
 | Season 5, Episode 13: Beat Your Heart OutOriginal Air Date—5 February 2009Cristina carries on an intense flirtation with Owen, Derek gets advice from everyone on how to propose, Izzie gets some tests done, and Bailey's promotion may stand in the way of a new career possibility. |
 | Season 5, Episode 14: Before and AfterOriginal Air Date—12 February 2009Owen runs into someone very special from his past. Izzie employs her fellow doctors in a medical game made to help teach the interns. Naomi, Sam and Addison rush Archer to Seattle Grace and meet with Derek and Mark to save his life. |
 | Season 5, Episode 15: An Honest MistakeOriginal Air Date—19 February 2009Addison and Derek differ on the treatment plan for their patient, Cristina discovers malpractice in high places, Izzie get bad news, and Mark spectacularly mistimes his confession. |
 | Season 5, Episode 16: I Will Follow You Into the DarkOriginal Air Date—12 March 2009Derek's malpractice deposition reveals an unhappy statistic, the interns finally diagnose 'Patient X', Karev stands up to two attendings to save a band geek, and when Webber shuts Miranda out completely she makes a call. |
 | Season 5, Episode 17: Stand by MeOriginal Air Date—19 March 2009Sloane's facial transplant fades to the background as the interns begin squabbling, Bailey attempts to reach Derek unexpectedly clear surgeons from the hospital, and Cristina juggles her first solo surgery with treating a resistant Izzie. |
 | Season 5, Episode 18: Elevator Love LetterOriginal Air Date—26 March 2009Owen's PTSD endangers Cristina, Izzie's illness leaves the residents dealing with guilt and anger - to her expense, and Derek's fear causes him to persevere for Meredith's answer. |
Season 5, Episode 19: Sweet SurrenderOriginal Air Date—23 April 2009Izzie bites off more than she can chew on her first day of chemotherapy, Mark and Derek are forced to work on the same patient, Meredith's plans for a simple wedding take a turn, and Karev finds himself split between worry over Izzie and excelling as a resident. |
 | Season 5, Episode 20: No Good at Saying Sorry (One More Chance)Original Air Date—30 April 2009Izzie's mother comes to town, a little girl shoots her father, triggering a conflict between Meredith and the chief, Thatcher reappears, and Callie gets her first taste of life without her trust fund. |
 | Season 5, Episode 21: What a Difference a Day MakesOriginal Air Date—7 May 2009A car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if the oversight is not. Meanwhile, Denny's return has Derek and Bailey searching for the cause, and the results will change the outcome of the day. |
 | Season 5, Episode 22: Here's to Future DaysOriginal Air Date—14 May 2009Izzie is torn over whether to have Derek's proposed brain surgery. A soldier on medical leave asks for a radical operation so he can return to active duty. The Chief tries to lure Bailey back to general surgery with a new toy, and Mark shifts into high gear with major life changes. |
 | Season 5, Episode 23: Now or NeverOriginal Air Date—14 May 2009Izzie's memory problems panic Alex, the team takes care of a John Doe who was hit by a bus, Bailey rethinks her pediatrics fellowship, and the hospital endures losses. |
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